PhD in Molecular imaging of microbial infections

Original title: PhD position in molecular imaging of microbial infections

With the recent introduction of the Vanco-800CW optical tracer and the Vanco-PQ-[18F]VE PET tracer, and their ongoing (pre)clinical translation, Groningen is taking the lead in imaging of Gram-positive infections. This PhD project will focus on expanding this initiative to the imaging of other clinically-relevant infections: with Gram-negative bacteria and fungi.

This project is a part of an Ubbo Emius-funded HTRIC consortium aimed at training the next generation of scientists in biomedical applications, bringing together specialists from chemistry, imaging, cancer biology, and physics to lay the foundation for imaging-guided pharmacotherapy.

What are you going to do?

The PhD student will design, synthesize and evaluate new imaging agents, study their photochemical behavior, and support their evaluation in biological models. They will be supported by a team, including PIs (Szymanski / van Dijl) with expertise in chemistry, photochemistry, clinical microbiology and imaging, and an ecosystem of colleagues with additional expertise in quantum calculations and photopharmacology. The broader HTRICxUEF consortium provides additional expertise in the use of high-energy radiation, nanomedical drug release, and other types of medical imaging.